The aniline intercalated MoO3 organic-inorganic hybrid compound as precursor was prepared. Then it was treated as Oxidative polymerization in air atmosphere at 120 ℃, the polyaniline intercalated MoO3 composite was constructed. Rhodamine B (RhB) was used as the target degradation material, and the photocatalytic of MoO3 composite was investigated The effects of light time, catalyst dosage and pH value on photocatalytic degradation efficiency were studied. The results show that the MoO3/PANI composites have good photocatalytic degradation effect on Rhodamine B under the conditions of pH value of 1~4, catalyst mass concentration of 0.30~0.40 g/L and illumination time of 2.0 h, moreover that the highest degradation rate is up to 98.00%.